SKINCEUTICALS Triple Lipid Restore 2:4:2

(22 customer reviews)


SKINCEUTICALS Triple Lipid Restore 2:4:2

Moisturiser. All skin types with signs of ageing.

As the first optimised 2:4:2 cholesterol-dominant ratio in an anti-aging treatment, Triple Lipid Restore 2:4:2 offers a high concentration with a unique lipid stabilisation system in a cosmetically elegant texture, the formula is lightweight and fast-absorbing, benefitting both aging skin and dry skin. The formula ingredients combine a maximised concentration of lipids

Size: 50 ml

We are expecting Triple Lipid Restore 2:4:2 to arrive from SkinCeuticals USA at the end of February. If necessary please contact our skincare therapists on live chat to find a suitable alternative in the meantime.

In stock

If you purchase this product you will earn 2736 SkinMiles if no other vouchers are used. Worth R273.60

Skin results and statements are based on clinical trials performed by the brand and individual results may vary.



How to use

How to use

Apply a small amount between fingertips, warm and melt the cream in circular motions. Apply twice daily to face, neck, and chest.

Features & Benefits

Features & Benefits

Lipids are intercellular natural compounds found in the epidermis. While there are many kinds of lipids in the skin: ceramides, cholesterol and fatty acids are the dominant forms.  These lipid components have been found in numerous scientific studies to play a crucial role in skin health, including healthy cell signaling, cell turnover, barrier function, and natural self-repair.

With age, lipid synthesis declines.  As a consequence, barrier function is weakened, imparting a reduction in skin’s natural repair in chronologically-aged skin.


  • Isolated from naturally-occurring organic wool wax
  • Stabilizes the structure of the stratum corneum, especially with respect to temperature changes
  • Provides a degree of fluidity to an otherwise rigid membrane system, a requirement for the elasticity of skin
  • A cholesterol-dominant treatment is proven to accelerate barrier recovery in aging skin to promote restoration of healthy skin function and self-repair


  • Skin-identical ceramides, possessing the same configuration as those in human skin
  • Unprecedented concentration of ceramide-1
  • Ceramide 1 and 3 work synergistically to restore barrier function and nourishment levels faster than either ceramides alone


  • Generated by molecular distillation of sunflower seed oil
  • High in linoleic acid (omega-6) and oleic acid (omega-9) in the form of triglycerides
  • Support overall lipid production


Triple Lipid Restore 2:4:2 is an anti-aging treatment to refill cellular lipids. This unique formulation utilizes an optimized concentration of ingredients to work synergistically on restoring skin’s external barrier and supporting natural self-repair for improvement in signs of accelerated aging.

Aging skin is increasingly susceptible to lipid depletion: the loss of natural fats in skin’s surface, present in the form of ceramides, cholesterol, and fatty acids. This lipid loss compromises skin’s natural protective barrier, resulting in signs of accelerated aging, as skin loses its ability to effectively self-repair. The visible effects in skin include roughness, dullness, uncomfortable tightness, and loss of facial fullness.

Triple Lipid Restore 2:4:2 is formulated with a maximized concentration of reparative lipids:

2% pure ceramides, 4% natural cholesterol and 2% fatty acids. This anti-aging lipid correction treatment contains the first cholesterol-dominant ratio to refill lipids, restore skin’s external barrier, and support natural repair, while potently nourishing aging skin. Triple Lipid Restore 2:4:2 has been clinically proven to improve skin’s smoothness, laxity, pore appearance, and overall radiance. It also:

  1. Stabilizes the structure of the stratum corneum
  2. Proven to increase hydration & barrier function
  3. Unprecedented concentration of ceramide-1
  4. High in linoleic acid (omega-6) and oleic acid (omega-9)
  5. Support overall lipid production
Key Ingredients

Key Ingredients

Key Ingredients

  • Essential Lipids: featuring natural cholesterol, pure ceramides and fatty acids, it restores skin’s youthful elasticity and hydration cycles
  • Vitamin E: supports natural cell repair and reproduction, helping defend against environmental damage
  • Essential Oils: packed with antioxidants to fight free-radical damage that is responsible for signs of aging.


qua/Water/Eau, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide 3, Helianthus Annuus Seed Oil Unsaponifiables/Sunflower Seed Oil Unsaponifiables, Bis-Peg-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, Peg-10 Dimethicone, Nylon-12, Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/Peg-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, Peg/Ppg-18/18 Dimethicone, Propylene Carbonate, Disodium Edta, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil/Lavender Oil, Rosmarinus Officinalis Leaf Oil/Rosemary Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil/Peppermint Oil, Sodium Citrate, Linalool, Isobutane, Ceramide Eop, Bht, Tocopherol, Limonene, D182888/1.

Reviews (22)

22 reviews for SKINCEUTICALS Triple Lipid Restore 2:4:2

  1. Iona

    Completely love this moisturiser – sadly as it is on the pricier side but I have tried others and none of them come close. It goes far further if you use a serum so something to keep in mind when investing.

  2. Bianca (verified owner)

    This is super hydrating moisturiser that absorbs well and leaves your skin feeling soft and radiant. Fine lines and overall texture improves over time – visible results!

  3. Anisha (verified owner)

    Excellent cream, my skin feels hydrated and it is looking radiant.

  4. Prinasha (verified owner)

    This is my go to moisturizer during winter. It hydrates the skin so well. Its a splurge but so worth the investment. My skin feels soft and smooth after I use this product.

  5. Meagan (verified owner)

    I have only been using this cream for a few days, AM and PM, and absolutely love it! It is so rich and soothes skin without causing it to feel heavy/greasy. Expensive but you use such a small amount. Will definitely continue to purchase.

  6. Zanele (verified owner)

    I just love how it feels on the skin. It’s so smooth, leaving my skin looking radiant and hydrated. I think I will have a glowing skin this winter 🤩

  7. Deidre (verified owner)

    This is such a fantastic product. It’s so soft on my skin and gives incredible results. It absorbs quickly, doesn’t feel heavy, and leaves me feeling great.

  8. Granite1234 (verified owner)

    I am fanatical about great skin care and have tried out so many products
    This is hands down the best moisturizer available
    It is truly a golden formula that achieves incredible results
    Highly recommended!!!

  9. jane (verified owner)

    I am blown away by this beautiful moisturizer. It’s amazing for a dry and sensitive skin and my skin feels plumper and hydrated after only using it for two weeks. I definitely will repurchase it again for winter as it is a superior product.

  10. Fatima1989 (verified owner)

    Best moisturizer ever for my skin, finally found my “can’t do without “ cream !

  11. Ashmita (verified owner)

    Just the best moisturizer I’ve ever used! Leaves my skin feeling soft, smooth and so hydrated. Love it

  12. Marinda66 (verified owner)

    I love the creamy texture and it blends easily & absorbs so well. Definitely nourish & hydrates my skin! Will buy again for sure

  13. Capetown1 (verified owner)

    This fabulous cream leaves my skin soft, supple and hydrated.
    Worth every cent when it comes to challenging winter dryness.
    Highly recommended.

  14. Keshnee (verified owner)

    Definitely helped my dry and sensitive skin. My skin feels smooth and no longer has the tight feeling associated with dehydrated skin. The feeling of hydration lasts all day.

  15. Charmaine (verified owner)

    I was hesitant to purchase this due to the cost, however this cream is worth every cent! I am on my second jar now and will keep buying it. My dry, sensitive skin has definitely improved with using this. I have bought products from SkinMiles for many years now and you can trust their recommendations. Their custmer service is also exceptional!

  16. jcstauch (verified owner)

    The video sold it to me – first time round.
    Second time , and third, and fourth… it was the product itself.
    It has the golden ration for lipid restoration and enhancing natural skin repair. It really does improve laxity, roughness, dullness and texture.
    My skin feels like it’s hit the golden lottery when I apply this Moisturized to the gills, but not oily at all. More resilient and yet beautifully supple.

  17. abigail (verified owner)

    I wish I could give this 6 stars. The best moisturiser Ive ever used. Its brillaint and does everything it promises to do. I work out daily and swim lots. This moisturiser looks after my skin and looks in all the other goodness from serums. I LOVE IT !

  18. Taryn Selmon (verified owner)

    I absolutely love this cream!
    Perfect creamy texture which blends easily & absorbs so well. Nourishes & hydrates normal skin. Since I have been using this cream (3 years) people often compliment me on how well hydrated my skin is.
    The handy spatula helps with taking just the right amount out of the glass jar, also helps make it last longer. But I cannot be without this top product!

  19. chrislazley (verified owner)

    I was a little suspect of this one. The research into lipid ratios by L’Oreal is incredible, and then Skinceuticals went and added lavender, peppermint and rosemary, which confuses me, since you’re simply adding needless potential for irritation.
    That being said, i’ve been impressed with it.
    It definitely works for dry skin and helps deal with retinoid use.

  20. Christelle Stone (verified owner)

    Have never had a better moisturiser than this one. I never had problems with my skin but now get even more compliments since I’ve been using this this one.
    Christelle (50)
    5 stars

    • Dr Alek Nikolic

      Thank you Christelle we appreciate the review and feedback. Kind regards Dr Alek

  21. Marinda66 (verified owner)

    Love the way my skin feel after using this moisturiser! Best I have used so far!

    • Dr Alek Nikolic

      Hi Marinda thank you for the feedback it is appreciated and will help future customers when considering the Triple Lipid Restore. Kind regards Dr Alek Nikolic

  22. annemarie

    this is a great moisturiser and I love what it does to my skin. I am 70 and have used SkinCeuticals for years and really trust their products

    • Dr Alek Nikolic

      Hi Anne Marie thank you for the feedback it is appreciated and will help future customers. Kind regards Dr Alek Nikolic

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Shipping & Delivery

Main Centre

Delivered to your door within 1-2 working days after payment is confirmed with Standard Delivery.

Regional Area

Delivered to your door within 3-5 working days after payment is confirmed with Standard Delivery.

Remote Area

Delivered to your door within 5-7 working days after payment is confirmed with Standard Delivery.

Delivery Options

  • FREE Delivery: On orders above R 750.00
  • Delivery Fee R120.00: On orders below R 750
  • I want to collect? - Collections welcome at our Pretoria office.


Main Centres: Johannesburg, Cape Town, Pretoria.
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